BDBM107702 US8598210, Table XV, 8::US8722895, 8: {[5-(4-Cyanophenyl)-3-hydroxypyridine-2- carbonyl]amino}-acetic acid

SMILES OC(=O)CNC(=O)c1ncc(cc1O)-c1ccc(cc1)[N+]#[C-]

InChI Key InChIKey=WESRXHMJQHLLSE-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 107702   

TargetVascular endothelial growth factor A(Homo sapiens (Human))
Akebia Therapeutics

US Patent
LigandPNGBDBM107702(US8598210, Table XV, 8 | US8722895, 8: {[5-(4-Cyan...)
Affinity DataEC50:  4.30E+3nMAssay Description:HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...More data for this Ligand-Target Pair
In DepthDetails US Patent